Plant toxin hailed as ‘new weapon’ in antibiotic war against bacteria

Published on January 31, 2023

Scientists say albicidin has allowed them to take a giant step forward to creating a powerful new range of antibacterial drugs

The new antibiotic – albicidin – attacks bacteria in a completely different way to existing drugs, a group of British, German and Polish scientists have revealed in a paper recently published in the journal Nature Catalysis. This suggests a new route could be exploited to tackle bacterial disease, they say.

More here: Plant toxin hailed as ‘new weapon’ in antibiotic war against bacteria | Antibiotics | The Guardian

The article cited is by Michalczyk, E., Hommernick, K., Behroz, I. et al. Molecular mechanism of topoisomerase poisoning by the peptide antibiotic albicidin. Nat Catal 6, 52–67 (2023). https://doi.org/10.1038/s41929-022-00904-1